Cannabidiol (CBD) Fact Sheet
Cannabidiol is a non-psychoactive cannabinoid and is the active ingredient in Dixie X medicinal hemp products from Dixie Elixirs & Edibles. The information here has been provided as a resource. Notes about citations and the research follow.
- Completely non-psychoactive. It is safe and non-toxic. Can never over-dose on CBD.
- It is the second most common cannabinoid in cannabis sativa and indica plants and the primary cannabinoid in hemp plants.
- Counters some of the negative effects of THC (ie. paranoia, intoxication, quick heartbeat (tachycardia) short term memory loss, lethargy/sedation, etc.)
- Combining THC and CBD have been found to increase clinical efficacy while reducing adverse effects, even with only trace amounts of THC added. (CBD works synergistically with THC, bolstering its medical effects while moderating its psychoactivity)
- Some medical benefits include:
- Has been found to relieve convulsions and other movement disorders. Is an anti-spasmodic and antiepileptic.
- At high doses (more than a few hundred mg) CBD can be sedative and helps insomniacs stay asleep longer. In low doses, CBD has been found to be alerting.
- It is also effective in reducing inflammation (anti-inflammatory), anxiety (anxiolytic), nausea (anti-emetic)
- Is a powerful pain reliever (analgesic) It is effective in both peripheral neuropathic pain and central pain
- It has been shown to inhibit cancer cell growth (anticarcinogenic)
- It is an immunomodulator and helps the immune system function more efficiently
- Is a neuroprotectant and a powerful antioxidant. It has applications in treatment for Alzheimer’s, Parkinsons, cerebral ischemia, and brain and nerve damage from stroke.
- It is an anti-psychotic and recent research has indicated it is effective in treatment of schizophrenia
- CBD could be effective in easing symptoms of a wide range of difficult-to-control conditions, including: rheumatoid arthritis, diabetes, alcoholism, PTSD, epilepsy, MS, antibiotic-resistant infections and neurological disorders, to name a few.
- Has been found to be effective in treating gastrointestinal disorders like IBD and Crohn’s Disease
CBD Informational Works Cited
Galal AM, Slade D, Gul W, El-Alfy, AT, Ferreira D, Elsohly, MA. Naturally Occuring and Related Synthetic Cannabinoids and their potential Therapeutic Applications. Recent Patents on CNS Drug Discovery. 2009; 4:112-136.
Gieringer, Dale, Rosenthal, Ed, Carter, Gregory T. Marijuana Medical Handbook. Oakland: Quick American, 2008.
Iversen, Leslie L. The Science of Marijuana. New York: Oxford University Press, 2008.
Mechoulam R, Hanus L. Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: Pharmacol. 2002; 42 (11 Suppl):11S-19S
Mechoulam R, Shvo Y. Hashish. 1. Structure of Cannabidiol. Tetrahedron. 1963; 19(12): 2073-8.
Russo E, Guy GW. A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. Med. Hypotheses. 2006;66(2): 234-46.
Zuardi AW. Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action. Rev Bras Psiquiatr. 2008 Sept; 30(3):271-80.
Peer review: is the process of evaluation and self-regulation of published works within a given professional field (in our case, science.) The evaluation involves a published work to be reviewed and critiqued by other qualified professionals in the same field. The evaluation and entire process are designed to maintain standards, improve performance of authors and most importantly confirm credibility.
In the case of peer reviewed journals, which are usually academic and scientific periodicals, peer review generally refers to the evaluation of articles prior to publication. But it can also refer to articles being reviewed following publication, as such articles often continue to be debated and studied for a longer period and by a broader audience.